TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

The diminished ability of cells to respond to the action of insulin in transporting glucose (sugar) from the bloodstream into muscle and other tissues.  2, record 1, English, - insulin%20resistance

Record number: 1, Textual support number: 1 CONT

Insulin resistance typically develops with obesity and heralds the onset of type 2 diabetes. It is as if insulin is "knocking" on the door of muscle. The muscle hears the knock, opens up, and lets glucose in. But with insulin resistance, the muscle cannot hear the knocking of the insulin (the muscle is "resistant"). The pancreas makes more insulin, which increases insulin levels in the blood and causes a louder "knock." Eventually, the pancreas produces far more insulin than normal and the muscles continue to be resistant to the knock. As long as one can produce enough insulin to overcome this resistance, blood glucose levels remain normal. Once the pancreas is no longer able to keep up, blood glucose starts to rise, initially after meals, eventually even in the fasting state. Type 2 diabetes is now overt.  2, record 1, English, - insulin%20resistance

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

[...] diminution de la réponse biologique à l'action de l'insuline.  3, record 1, French, - insulinor%C3%A9sistance

Record number: 1, Textual support number: 1 CONT

L'insulinorésistance se définit comme un état de diminution de la réponse cellulaire et tissulaire à l'insuline. Associée à la diminution de la capacité sécrétoire de l'insuline, elle conduit au développement du diabète de type 2.  2, record 1, French, - insulinor%C3%A9sistance

Record number: 1, Textual support number: 2 CONT

L'insulinorésistance est liée à un risque métabolique et cardiovasculaire accru dans le contexte du «syndrome d'insulinorésistance» (ou «syndrome plurimétabolique») [...]  3, record 1, French, - insulinor%C3%A9sistance

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Disminución de la efectividad de la insulina para reducir los niveles de azúcar en la sangre.  1, record 1, Spanish, - resistencia%20a%20la%20insulina

Record number: 1, Textual support number: 1 OBS

Se define arbitrariamente por el requerimiento de 200 unidades o más de insulina por día para evitar la hiperglucemia o la cetosis; usualmente se debe a la fijación de la insulina a anticuerpos pero también se producen anormalidades de los receptores para insulina situados en la superficie celular; está asociada con obesidad, cetoacidosis, infección y ciertas afecciones poco frecuentes.  1, record 1, Spanish, - resistencia%20a%20la%20insulina